Symbol
Name
ID

Grik2
glutamate receptor, ionotropic, kainate 2 (beta 2)
MGI:95815

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Torticollis

Gliosis

Cerebellar atrophy

Neuronal loss in central nervous system

Gait ataxia

Bradykinesia

Chorea

Involuntary movements

Myoclonus

Kinetic tremor

Postural tremor

Depression

Reduced social reciprocity

Personality changes

Dementia

Intellectual disability

Intellectual disability, mild

Hyperreflexia

Global developmental delay

Seizure

Atonic seizure

Disease(s) Associated with GRIK2

autosomal recessive intellectual developmental disorder 6

Huntington's disease

Mouse Phenotypes		decreased susceptibility to pharmacologically induced seizures	increased susceptibility to pharmacologically induced seizures	abnormal single cell response	abnormal CNS synaptic transmission	abnormal excitatory postsynaptic potential	abnormal glutamate-mediated receptor currents	abnormal long-term potentiation	reduced long-term potentiation	decreased paired-pulse facilitation
Availability	Mouse Genotype			abnormal single cell response	abnormal CNS synaptic transmission	abnormal excitatory postsynaptic potential	abnormal glutamate-mediated receptor currents	abnormal long-term potentiation	reduced long-term potentiation	decreased paired-pulse facilitation
	Grik2^tm1Bvis/Grik2^tm1Bvis
	Grik2^tm1Sfh/Grik2^tm1Sfh

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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